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13) If the human genome contains 30,000 genes, and the mutation rate @ each of these loci is 10-5 per gamete formed, what is the average # of new mutations that exist in each individual? If the current population is 4.3 billion people, how many newly arisen mutations exist in the current populace? 15) Speculate on which types of observed mutations are likely to give rise to les severe symptoms of CF, including only minor PI. Of the 300 sequence alterations, a # of them found within the exon regions of the CFTR gene do not give rise to cystic fibrosis.
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