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Mythili Duvvuri 09/05/2003 His 101 Columbian Exchange The most tragic trade with the three contents Europe, Africa and North America was the consequence of human contact. Around the time of the exploration a lot of Europeans lost their lives to diseases. The Black Death, a disease that evolved around the Fourteenth Century had decreased a third of Europe’s population. There were other serious diseases such as small pox, measles and typhus, which had very devastating results. But luckily the Europeans found ways to resist infections. Columbus and the Europeans explore and discovered the Native Americans, in an environment where contagious disease was never a threat until the Anglo-Saxons arrived. Then much more disease had spread faster and it was more deadly to the Native Americans. In 1492 an estimate of people that lived in America was from a high of 25 million to a low of 1 million.
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