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AU: Author Sankhla, D; Davis, TD; Sankhla, N; Upadhyaya, A; Smith, BN AF: Author Affilition Bot. Dep., Univ. Jodhpur, Jodhpur 342001, India SO: Source BIOCHEM. PHYSIOL. PFLANZ. BPP., vol. 180, no. 8, pp. 625-628, 1985 AB: Abstract 2-(3,4-dichlorophenoxy)-triethylamine (DCPTA) increased betacyanin efflux from beet root discs possibly by destabilizing the cell membrane. Alcohol and DCPTA act additively in influencing solute efflux. Polyamines, which stabilize the membrane, not only arrested the efflux of betacyanin when used alone, but also counteracted the effect of DCPTA. Kinetic analysis of the data suggests that DCPTA and spermine bind at different sites on the plasmalemma. LA: Language English SL: Summary Language English PY: Publication Year 1985 PT: Publication Type Journal Article DE: Descriptors 2-(3,4-dichlorophenoxy)-triethylamine; betacyanin; roots; Beta vulgaris ID: Identifiers effects on; efflux CL: Classification M 13117 Higher plants SF: Subfile Biochemistry Abstracts 1: Biological Membranes (till 1993) AN: Accession Number 1394725 TI: Title Differential effect of catecholamines and MPP super(+) on membrane permeability in brain mitochondria and cell viability in PC12 cells AU: Author Lee, CS; Han, JH; Jang, YY; Song, JH; Han, ES AF: Affiliation Department of Pharmacology, College of Medicine, Chung-Ang University, Seoul 156-756, South Korea, mailto:leecs@cau.ac.kr SO: Source Neurochemistry International [Neurochem. Int.]. Vol. 40, no. 4, pp. 361-369. Apr 2002. IS: ISSN 0197-0186 AB: Abstract The present study examined the effect of dopamine, 6-hydroxydopamine (6-OHDA), and MPP super(+) on the membrane permeability transition in brain mitochondria and on viability in PC12 cells. Dopamine and 6-hydroxydopamine induced the swelling and membrane potential change in mitochondria, which was inhibited by addition of antioxidant enzymes, SOD and catalase. In contrast, antioxidant enzymes did not reduce the effect of MPP super(+) on mitochondrial swelling and membrane potential. Catecholamines enhanced the Ca super(2+) uptake and release by mitochondria, and the addition of MPP super(+) induced Ca super(2+) release.
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